| |
|
|
| Registros recuperados : 17 | |
| 2. |  | KAWAMOTO, T. S.; VIANA, J. H. M.; FARIA, O. A. C.; FIGUEIREDO, R. A. Ovarian characteristics and somatic development in 2 to 5 months old female Nelore (Bos taurus indicus) calves. Animal Reproduction, v. 15, Suppl.1, p.1086, 2018. Edição dos resumos do 10th International Ruminant Reproduction Symposium (IRRS 2018), 2018., Foz do Iguaçu-PR. CBRA.| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
|    |
| 4. | | FARIA, O. A. C.; CAIXETA, F. M.; DIAS, L. R. O.; SPRÍCIGO, J. F. W.; DODE, M. A. N. Effect of the anticipation of intrafollicular transfer of immature oocytes (IFIOT) in the nuclear maturation of bovine oocyte. Animal Reproduction, v. 16, n. 3, p. 587, Jul./Sept. 2019. Edição dos Proceedings of the 33nd Annual Meeting of the Brazilian Embryo Technology Society (SBTE); Ilha da Comandatuba, BA, Brazil, August 15th to 19th, 2019.| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
|  |
| 6. | | VIANA, J. H. M.; PEREIRA, N. E. S.; FARIA, O. A. C.; DIAS, L. R. O.; OLIVEIRA, E. R.; FERNANDES, C. A. C.; SIQUEIRA, L. G. B. Active immunization against GnRH as an alternative therapeutic approach for the management of Bos indicus oocyte donors diagnosed with chronic cystic ovarian disease. Theriogenology, v. 172, p. 133-141, 2021.| Biblioteca(s): Embrapa Gado de Leite; Embrapa Recursos Genéticos e Biotecnologia. |
| |
| 7. | | DIAS, L. R. O.; FARIA, O. A.; CAIXETA, F. M. C.; RODRIGUES, S. de A. D.; SPRÍCIGO, J. F. W.; DODE, M. A. N. Nuclear maturation of bovine oocytes submitted to the in vivo maturation using intrafollicular transfer of immature oocytes (IFIOT) system. Animal Reprodroduction, v. 14, n. 3, p. 761, Jul./Sept. 2017. Proceedings of the 31st Annual Meeting of the Brazilian Embryo Technology Society (SBTE); Cabo de Santo Agostinho, PE, Brazil, August 17th to 19th, 2017. Abstracts| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
| |
| 8. | | KAWAMOTO, T. S.; PONTELO, T. P.; FARIA, O. A. C. de; FIDELIS, A. A. G.; DODE, M. A. N.; VIANA, J. H. M.; FIGUEIREDO, R. A. OPU and IVEP from non-stimulated 2-4 and 8-10 months old Nelore (Bos taurus indicus) donors. Animal Reproduction v.16, n.3, p.597, Jul./Sept. 2019. Edição dos Proceedings of the 33nd Annual Meeting of the Brazilian Embryo Technology Society (SBTE); Ilha da Comandatuba, BA, Brazil, August 15th to 19th, 2019.| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
| |
| 9. | | KAWAMOTO, T. S.; VIANA, J. H. M.; PONTELO, T. P.; FRANCO, M. M.; FARIA, O. A. C. de; FIDELIS, A. A. G.; VARGAS, L. N.; FIGUEIREDO, R. A. Dynamics of the reproductive changes and acquisition of Oocyte competence in Nelore (Bos taurus indicus) Calves during the early and intermediate prepubertal periods. Animals, v. 12, n. 15, 2022. 2137.| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
| |
| 10. | | SILVA, V. A.; FARIA, O. A. C.; DIAS, L. R. O.; CAIXETA, F. M. C.; SPRÍCIGO, J. F. W.; DODE, M. A. N. Inhibition of meiosis resumption in bovine oocytes to be used in the intrafollicular transfer of immature oocyte (TIFOI). Animal Reproduction, v. 15, n. 3, p. 456, Jul./Sept. 2018. Proceedings of the 32nd Annual Meeting of the Brazilian Embryo Technology Society (SBTE); Florianópolis, SC, Brazil, August 16th to 18th, 2018. Abstracts.| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
| |
| 11. | | DIAS, L. R. O.; SILVA, V. A. O.; FARIA, O. A. C.; CAIXETA, F. M. C.; SPRÍCIGO, J. F. W.; DODE, M. A. N. Embryos production from bovine oocytes matured in vivo using intrafollicular transfer of immature oocytes (TIFOI). Animal Reproduction, v. 15, n. 3, p. 428, Jul./Sept. 2018. Proceedings of the 32nd Annual Meeting of the Brazilian Embryo Technology Society (SBTE); Florianópolis, SC, Brazil, August 16th to 18th, 2018. Abstracts.| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
| |
| 12. | | KAWAMOTO, T. S.; VIANA, J. H. M.; PONTELO, T. P.; FARIA, O. A. C.; FIDELIS, A. A. G.; DODE, M. A. N.; VARGAS, L. N.; FIGUEIREDO, R. A. Features and development potential of oocytes collected from Nelore (Bos tuarus indicus) calves and the early and late prepubertal phase. Reproduction, Fertility and Development, v. 34, n. 2, p. 302, 2022 Edição dos Proceedings of the 48th International Embryo Technology Society Annual Meeting, Savannah, 2022.| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
| |
| 13. | | FARIA, O. A. C.; KAWAMOTO, T. S.; DIAS, L. R. O.; FIDELIS, A. A. G.; LEME, L. O.; CAIXETA, F. M. C.; GOMES, A. C. M. M.; SPRÍCIGO, J. F. W.; DODE, M. A. N. Maturation system affects lipid accumulation in bovine oocytes. Reproduction, Fertility and Development, v. 33, n. 5, 372-380, 2021.| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
| |
| 14. | | SANTOS, I. R.; TOLEDO, R. B.; FARIA, O. A. C.; LEME, L. O.; DODE, M. A. N.; GUIMARAES JUNIOR, R.; MAGNABOSCO, C. de U.; BONFIM JUNIOR, S.; EIFERT, E. da C.; MARTINS, C. F. Effect of two different feeding strategies on prepubertal Nellore Heifer's growth performance and oocytes and in vitro embryo production. Animal Reproduction, v. 19, n. 1, 2022. Abstract ISABR 2020/2021.| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
| |
| 15. | | SANTOS, I. R.; TOLEDO, R. B.; FARIA, O. A. C.; LEME, L. O.; DODE, M. A. N.; GUIMARAES JUNIOR, R.; MAGNABOSCO, C. de U.; BONFIM JUNIOR, S.; EIFERT, E. da C.; MARTINS, C. F. Effect of two different feeding strategies on prepubertal Nellore Heifer's growth performance and oocytes and in vitro embryo production. Animal Reproduction, v. 19, n. 1, 2022. Abstract ISABR 2020/2021.| Biblioteca(s): Embrapa Cerrados. |
| |
| 16. | | SILVA, T. C. F.; DODE, M. A. N.; BRAGA, T. F.; MARQUES, M. G.; VARGAS, L. N.; FARIA, O. A. C. de; SOUZA, A. P. de; ALBRING, D.; CAETANO, A. R.; FRANCO, M. M. Cumulus-oocyte complexes from sows show differences in lipid metabolism compared to cumulus-oocyte complexes from prepubertal gilts during in vitro maturation. Molecular Reproduction & Development, v. 90, n. 5, p. 323-335. 2023.| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia; Embrapa Suínos e Aves. |
| |
| 17. | | TOLEDO, R. B. de; FARIA, O. A. C. de; LEME, L. O.; MAGNABOSCO, C. de U.; GUIMARAES JUNIOR, R.; EIFERT, E. da C.; SANTOS, I. R. dos; OLIVEIRA, R. V.; DODE, M. A. N.; MALAQUIAS, J. V.; PIVATO, I.; MARTINS, C. F. Effect of food supplementation on in vitro embryo production and growth performance in prepubertal Nelore heifers. Animal Biotechnology, 2023.| Biblioteca(s): Embrapa Cerrados; Embrapa Recursos Genéticos e Biotecnologia. |
| |
| Registros recuperados : 17 | |
|
|
|
 | Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Leite. Para informações adicionais entre em contato com cnpgl.biblioteca@embrapa.br. |
Registro Completo
|
Biblioteca(s): |
Embrapa Gado de Leite; Embrapa Recursos Genéticos e Biotecnologia. |
|
Data corrente: |
03/07/2021 |
|
Data da última atualização: |
31/08/2021 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Circulação/Nível: |
A - 2 |
|
Autoria: |
VIANA, J. H. M.; PEREIRA, N. E. S.; FARIA, O. A. C.; DIAS, L. R. O.; OLIVEIRA, E. R.; FERNANDES, C. A. C.; SIQUEIRA, L. G. B. |
|
Afiliação: |
JOAO HENRIQUE MOREIRA VIANA, Cenargen; NATHALIA ELLEN SOUSA PEREIRA, UNB; OTAVIO AUGUSTO COSTA FARIA, UNB; LUZIA RENATA OLIVEIRA DIAS, UNB; EDUARDO RAMOS OLIVEIRA, UNIFENAS; CARLOS ANTONIO CARVALHO FERNANDES, UNIFENAS; LUIZ GUSTAVO BRUNO SIQUEIRA, CNPGL. |
|
Título: |
Active immunization against GnRH as an alternative therapeutic approach for the management of Bos indicus oocyte donors diagnosed with chronic cystic ovarian disease. |
|
Ano de publicação: |
2021 |
|
Fonte/Imprenta: |
Theriogenology, v. 172, p. 133-141, 2021. |
|
DOI: |
https://doi.org/10.1016/j.theriogenology.2021.06.014 |
|
Idioma: |
Inglês |
|
Conteúdo: |
The aim of this study was to evaluate the effect of active immunization against GnRH in Nelore (Bos indicus) cows repeatedly used as oocyte donors that developed chronic cystic ovarian disease (COD). In the first experiment, ovarian and uterine features were first compared between COD cows (n ¼ 15) and healthy cows (n ¼ 22, cycling control group) from the same breed and herd. Cows with COD had a greater number of large (P < 0.0001) and medium follicles (P < 0.01) but lesser small follicles (P < 0.05) than cycling controls. Mucometra was diagnosed in 73.3% of COD cows, but in none of the controls. No difference in average thickness of the endometrium was detected between groups; however, endometrial thickness and mucometra score were negatively correlated (R ¼ 0.73, P ¼ 0.0029) in COD cows. In the second experiment, COD cows were randomly allocated into two experimental groups, which received two 1.0 mL SC injections of either an anti-GnRH vaccine (COD immunized group, n ¼ 8) or saline (COD control group, n ¼ 7), given 28 days apart. Cows were examined weekly by transrectal ultrasonography during nine consecutive weeks after the first injection to evaluate the number and distribution of follicles among size classes, endometrial thickness, and presence of clinical mucometra. Vaccination against GnRH resulted in a progressive suppression of follicle growth and a reduction in the average size of the largest follicle, as well as in the number of large follicles (P < 0.01) in COD immunized cows compared with COD controls from week 7 onwards. Conversely, the number of small follicles in the COD immunized group increased after week 5 and was greater (P ¼ 0.0023) than controls on week 9. Endometrial thickness and mucometra score were not affected (P > 0.05) by immunization against GnRH. In the third experiment, the COD immunized cows with effective suppression of follicle growth four weeks after the 2nd injection (n ¼ 6) were submitted to three consecutive ovum pick-up (OPU) sessions (weeks 10, 11, and 12) for in vitro embryo production (IVEP). Cumulus-oocyte complexes (COC) collected from slaughterhouse ovaries were used as controls for IVEP. COD cows with produced 25.0 ± 3.8 COC per OPU session with no apparent detrimental effect of anti-GnRH vaccine on oocyte developmental potential in vitro, i.e., we observed similar cleavage rate (P ¼ 0.5914) and greater blastocyst rate (P ¼ 0.0177) in immunized cows compared with COC from slaughterhouse controls. Finally, in the fourth experiment wave emergence and follicular dynamics after follicle ablation were compared between COD immunized cows with effective suppression of follicle growth and a subset (n ¼ 6) of the cycling, control group. No follicles grew beyond 4 mm diameter after follicle ablation in the COD immunized group, whereas a normal follicular wave emergence occurred in cycling controls. Antral follicle count was similar between cycling controls and COD immunized groups at 24 h and 96 h post-follicle ablation (P > 0.05), but greater in cycling controls at 48 h and 72 h post-follicle ablation (P < 0.05). In summary, our results suggest that active immunization against GnRH is effective to induce the regression of follicular cysts as well as increase the number of small follicles growing on the ovaries, in oocyte donors diagnosed with chronic COD, with no apparent negative effect on oocyte developmental potential in vitro. MenosThe aim of this study was to evaluate the effect of active immunization against GnRH in Nelore (Bos indicus) cows repeatedly used as oocyte donors that developed chronic cystic ovarian disease (COD). In the first experiment, ovarian and uterine features were first compared between COD cows (n ¼ 15) and healthy cows (n ¼ 22, cycling control group) from the same breed and herd. Cows with COD had a greater number of large (P < 0.0001) and medium follicles (P < 0.01) but lesser small follicles (P < 0.05) than cycling controls. Mucometra was diagnosed in 73.3% of COD cows, but in none of the controls. No difference in average thickness of the endometrium was detected between groups; however, endometrial thickness and mucometra score were negatively correlated (R ¼ 0.73, P ¼ 0.0029) in COD cows. In the second experiment, COD cows were randomly allocated into two experimental groups, which received two 1.0 mL SC injections of either an anti-GnRH vaccine (COD immunized group, n ¼ 8) or saline (COD control group, n ¼ 7), given 28 days apart. Cows were examined weekly by transrectal ultrasonography during nine consecutive weeks after the first injection to evaluate the number and distribution of follicles among size classes, endometrial thickness, and presence of clinical mucometra. Vaccination against GnRH resulted in a progressive suppression of follicle growth and a reduction in the average size of the largest follicle, as well as in the number of large follicles (P < 0.01) in COD ... Mostrar Tudo |
|
Palavras-Chave: |
Follicle growth suppression; GnRH vaccine; In vitro embryo production; Nelore breed. |
|
Thesagro: |
Bovino; Doença Animal; Gado Nelore. |
|
Categoria do assunto: |
--
L Ciência Animal e Produtos de Origem Animal |
|
Marc: |
LEADER 04414naa a2200289 a 4500
001 2133972
005 2021-08-31
008 2021 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1016/j.theriogenology.2021.06.014$2DOI
100 1 $aVIANA, J. H. M.
245 $aActive immunization against GnRH as an alternative therapeutic approach for the management of Bos indicus oocyte donors diagnosed with chronic cystic ovarian disease.$h[electronic resource]
260 $c2021
520 $aThe aim of this study was to evaluate the effect of active immunization against GnRH in Nelore (Bos indicus) cows repeatedly used as oocyte donors that developed chronic cystic ovarian disease (COD). In the first experiment, ovarian and uterine features were first compared between COD cows (n ¼ 15) and healthy cows (n ¼ 22, cycling control group) from the same breed and herd. Cows with COD had a greater number of large (P < 0.0001) and medium follicles (P < 0.01) but lesser small follicles (P < 0.05) than cycling controls. Mucometra was diagnosed in 73.3% of COD cows, but in none of the controls. No difference in average thickness of the endometrium was detected between groups; however, endometrial thickness and mucometra score were negatively correlated (R ¼ 0.73, P ¼ 0.0029) in COD cows. In the second experiment, COD cows were randomly allocated into two experimental groups, which received two 1.0 mL SC injections of either an anti-GnRH vaccine (COD immunized group, n ¼ 8) or saline (COD control group, n ¼ 7), given 28 days apart. Cows were examined weekly by transrectal ultrasonography during nine consecutive weeks after the first injection to evaluate the number and distribution of follicles among size classes, endometrial thickness, and presence of clinical mucometra. Vaccination against GnRH resulted in a progressive suppression of follicle growth and a reduction in the average size of the largest follicle, as well as in the number of large follicles (P < 0.01) in COD immunized cows compared with COD controls from week 7 onwards. Conversely, the number of small follicles in the COD immunized group increased after week 5 and was greater (P ¼ 0.0023) than controls on week 9. Endometrial thickness and mucometra score were not affected (P > 0.05) by immunization against GnRH. In the third experiment, the COD immunized cows with effective suppression of follicle growth four weeks after the 2nd injection (n ¼ 6) were submitted to three consecutive ovum pick-up (OPU) sessions (weeks 10, 11, and 12) for in vitro embryo production (IVEP). Cumulus-oocyte complexes (COC) collected from slaughterhouse ovaries were used as controls for IVEP. COD cows with produced 25.0 ± 3.8 COC per OPU session with no apparent detrimental effect of anti-GnRH vaccine on oocyte developmental potential in vitro, i.e., we observed similar cleavage rate (P ¼ 0.5914) and greater blastocyst rate (P ¼ 0.0177) in immunized cows compared with COC from slaughterhouse controls. Finally, in the fourth experiment wave emergence and follicular dynamics after follicle ablation were compared between COD immunized cows with effective suppression of follicle growth and a subset (n ¼ 6) of the cycling, control group. No follicles grew beyond 4 mm diameter after follicle ablation in the COD immunized group, whereas a normal follicular wave emergence occurred in cycling controls. Antral follicle count was similar between cycling controls and COD immunized groups at 24 h and 96 h post-follicle ablation (P > 0.05), but greater in cycling controls at 48 h and 72 h post-follicle ablation (P < 0.05). In summary, our results suggest that active immunization against GnRH is effective to induce the regression of follicular cysts as well as increase the number of small follicles growing on the ovaries, in oocyte donors diagnosed with chronic COD, with no apparent negative effect on oocyte developmental potential in vitro.
650 $aBovino
650 $aDoença Animal
650 $aGado Nelore
653 $aFollicle growth suppression
653 $aGnRH vaccine
653 $aIn vitro embryo production
653 $aNelore breed
700 1 $aPEREIRA, N. E. S.
700 1 $aFARIA, O. A. C.
700 1 $aDIAS, L. R. O.
700 1 $aOLIVEIRA, E. R.
700 1 $aFERNANDES, C. A. C.
700 1 $aSIQUEIRA, L. G. B.
773 $tTheriogenology$gv. 172, p. 133-141, 2021.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Gado de Leite (CNPGL) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
Fechar
|
| Nenhum registro encontrado para a expressão de busca informada. |
|
|
